Friday, February 1, 2013

Stimulation of TRPV1 by Green Laser Light.




HubMed - Laser Acupuncture





Stimulation of TRPV1 by Green Laser Light.



Evid Based Complement Alternat Med. 2012; 2012: 857123
Gu Q, Wang L, Huang F, Schwarz W

Low-level laser irradiation of visible light had been introduced as a medical treatment already more than 40 years ago, but its medical application still remains controversial. Laser stimulation of acupuncture points has also been introduced, and mast-cells degranulation has been suggested. Activation of TRPV ion channels may be involved in the degranulation. Here, we investigated whether TRPV1 could serve as candidate for laser-induced mast cell activation. Activation of TRPV1 by capsaicin resulted in degranulation. To investigate the effect of laser irradiation on TRPV1, we used the Xenopus oocyte as expression and model system. We show that TRPV1 can functionally be expressed in the oocyte by (a) activation by capsaicin (K(1/2) = 1.1 μM), (b) activation by temperatures exceeding 42°C, (c) activation by reduced pH (from 7.4 to 6.2), and (d) inhibition by ruthenium red. Red (637 nm) as well as blue (406 nm) light neither affected membrane currents in oocytes nor did it modulate capsaicin-induced current. In contrast, green laser light (532 nm) produced power-dependent activation of TRPV1. In conclusion, we could show that green light is effective at the cellular level to activate TRPV1. To which extend green light is of medical relevance needs further investigation.








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www.djorin.com - If you've tried acupuncture before, electro acupuncture will provide even more relief. The stimulation of your acupoints through the use of electricity increases the healing effect. You may be able have the result that you want after just one treatment or it may take longer if you have a chronic condition. Electro Acupuncture Equipment - Automatic Treatment - Auto-selection of Acupoints - Electro Acupuncture Treatment Without Needles Medicomat stimulator provides the therapy through the acupuncture points in projecting parts of body, dredging the channels and points, readjusting the functions of the pathological organs by strengthening the cell biological vitality, increasing the blood circulations, building a strong immune system, keeping the body in a balanced environment. Distributors wanted
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HubMed - far infrared therapy





Length polymorphisms of heme oxygenase-1 determine the effect of far-infrared therapy on the function of arteriovenous fistula in hemodialysis patients: a novel physicogenomic study.



Nephrol Dial Transplant. 2013 Jan 22;
Lin CC, Chung MY, Yang WC, Lin SJ, Lee PC

BackgroundThe objective of this study was to evaluate the interaction between the length polymorphism of the guanosine thymidine repeat [(GT)(n)] in the heme oxygenase-1 (HO-1) gene and far-infrared (FIR) therapy on access flow (Qa) and arteriovenous fistula (AVF) patency in hemodialysis (HD) patients.MethodsA total of 280 HD patients were randomized into a control group (n = 141) and the FIR group (n = 139) who received 40 min of FIR therapy three times weekly for a year during the study period from May 2005 to December 2007. Access flow was measured during HD. The [(GT)(n)] was determined with the definition of long (L) allele as [(GT)(n)] ≥ 30 and short (S) allele as [(GT)(n)] < 30.ResultsThe Qa decreased from S/S to S/L and further to the L/L group but increased by FIR therapy with the highest Qa increase in the S/S group. The incidence of AVF malfunction decreased both from the L/L, S/L to S/S group (32.4 versus 17.2 versus 10.9%, P = 0.007) and from the control group to FIR group (27.5 versus 12.6%, P = 0.004). Significant associations were found between AVF malfunction and the following factors (hazard ratio, P-value): a past history of AVF malfunction (2.45, P = 0.044), FIR therapy (0.369, P = 0.03) and L/L genotypes of HO-1 (2.531 versus S/S + S/L genotypes). The 1-year unassisted patency decreased from 91.9 and 77.6% in S/S and S/L subgroups with and without FIR therapy to 75.8 and 60% for L/L subgroup with and without FIR therapy, respectively (P < 0.001).ConclusionsFIR therapy improves Qa and patency of AVF in HD patients, with the best protective effect in those with S/S genotype of HO-1.







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