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HubMed - Low Level Laser therapy
Low level laser therapy (AlGaInP) applied at 5J/cm2 reduces the proliferation of Staphylococcus aureus MRSA in infected wounds and intact skin of rats*.
An Bras Dermatol. 2013 Feb; 88(1): 50-5
Silva DC, Plapler H, Costa MM, Silva SR, Sá Mda C, Silva BS
Laser therapy is a low cost, non-invasive procedure with good healing results. Doubts exist as to whether laser therapy action on microorganisms can justify research aimed at investigating its possible effects on bacteria-infected wounds.To assess the effect of low intensity laser on the rate of bacterial contamination in infected wounds in the skin of rats.An experimental study using 56 male Wistar rats. The animals were randomly divided into eight groups of seven each. Those in the "infected" groups were infected by Staphylococcus aureus MRSA in the dorsal region. Red laser diode (AlGaInP) 658nm, 5J/cm2 was used to treat the animals in the "treated" groups in scan for 3 consecutive days. Samples were drawn before inoculating bacteria and following laser treatment. For statistical analysis we used the nonparametric Wilcoxon (paired data) method with a significance level of p <0.05.The statistical analysis of median values showed that the groups submitted to laser treatment had low bacterial proliferation.The laser (AlGaInP), with a dose of 5J/cm2 in both intact skin and in wounds of rats infected with Staphylococcus aureus MRSA, is shown to reduce bacterial proliferation.
HubMed - holistic Health
Turning disciplinary knowledge into solutions.
J Adolesc Health. 2013 May; 52(5 Suppl): S98-S102
Gehlert S
Turning disciplinary knowledge about preadolescents' and adolescents' exposure to risk factors for cancer as adults into solutions for preventing such an outcome requires that investigators from a variety of backgrounds and disciplines come together to share knowledge. Optimally, these collaborations would occur across two dimensions: (1) transdisciplinary, from the molecular or cellular level (e.g., animal studies of endocrine disruption) to the societal level (e.g., economic studies related to state tobacco policies); and (2) translational, using basic research findings in clinical and other sciences to implement prevention programs and public policy. Only when collaboration is commonplace can the disparate groups of investigators working on cancer prevention during preadolescence and adolescence gain a holistic picture of the risk factors, inform one another's work, and learn what we need to know to devise successful interventions for preventing cancer. Working transdisciplinarily also helps to ensure that messages to health professionals, policymakers, the news media, and the public are consistent and coordinated. At present, those investigating preadolescent and adolescent risk for adult cancer disseminate their knowledge individually, thus missing the opportunity to synthesize knowledge, coordinate dissemination, and implement prevention programs. In this article, we distinguish multidisciplinary, interdisciplinary, and transdisciplinary approaches; argue for the benefits of a transdisciplinary approach to devising successful solutions; and explore how to achieve transdisciplinary functioning.
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